| 1 |  Gran Premio de Argentina 1978 | Juan y Oscar Gálvez | 1978-01-15 | Mario Andretti | Lotus | Mario Andretti | 52 | 310.336 | — | |
| 2 |  Grande Prêmio do Brasil 1978 | Nelson Piquet | 1978-01-29 | Carlos Reutemann | Ferrari | Ronnie Peterson | 63 | 316.953 | — | |
| 3 |  The Citizen and Asseng Grand Prix of South Africa 1978 | Kyalami | 1978-03-04 | Ronnie Peterson | Lotus | Niki Lauda | 78 | 320.112 | — | |
| 4 |  1978 Long Beach Grand Prix | Long Beach | 1978-04-02 | Carlos Reutemann | Ferrari | Carlos Reutemann | 80 | 260.080 | — | |
| 5 |  Grand Prix de Monaco 1978 | Monaco | 1978-05-07 | Patrick Depailler | Tyrrell | Carlos Reutemann | 75 | 248.400 | — | |
| 6 |  1978 Belgian Grand Prix | Zolder | 1978-05-21 | Mario Andretti | Lotus | Mario Andretti | 70 | 298.340 | — | |
| 7 |  Gran Premio de España 1978 | Jarama | 1978-06-04 | Mario Andretti | Lotus | Mario Andretti | 75 | 255.300 | — | |
| 8 |  Sveriges Grand Prix 1978 | Anderstorp Raceway | 1978-06-17 | Niki Lauda | Brabham | Mario Andretti | 70 | 282.170 | — | |
| 9 |  Grand Prix de France 1978 | Paul Ricard | 1978-07-02 | Mario Andretti | Lotus | John Watson | 54 | 313.686 | — | |
| 10 |  1978 John Player British Grand Prix | Brands Hatch | 1978-07-16 | Carlos Reutemann | Ferrari | Ronnie Peterson | 76 | 319.732 | — | |
| 11 |  Grosser Preis von Deutschland 1978 | Hockenheimring | 1978-07-30 | Mario Andretti | Lotus | Mario Andretti | 45 | 305.505 | — | |
| 12 |  Grosser Preis von Österreich 1978 | Red Bull Ring | 1978-08-13 | Ronnie Peterson | Lotus | Ronnie Peterson | 54 | 320.868 | — | RF |
| 13 |  Grote Prijs van Nederland 1978 | Zandvoort | 1978-08-27 | Mario Andretti | Lotus | Mario Andretti | 75 | 316.950 | — | WCC |
| 14 |  Gran Premio d'Italia 1978 | Monza | 1978-09-10 | Niki Lauda | Brabham | Mario Andretti | 40 | 232.000 | — | WDC RF |
| 15 | 1978 Toyota United States Grand Prix | Watkins Glen | 1978-10-01 | Carlos Reutemann | Ferrari | Mario Andretti | 59 | 320.665 | — | |
| 16 |  Grand Prix du Canada 1978 | Gilles Villeneuve | 1978-10-08 | Gilles Villeneuve | Ferrari | Jean-Pierre Jarier | 70 | 315.000 | — | |