| 1 |  Formula 1 Gulf Air Bahrain Grand Prix 2021 | Bahrain | 2021-03-28 | Lewis Hamilton | Mercedes | Max Verstappen | 56 | 302.826 | 40 | SC |
| 2 |  Formula 1 Pirelli Gran Premio del Made in Italy e dell'Emilia Romagna 2021 | Enzo e Dino Ferrari | 2021-04-18 | Max Verstappen | Red Bull | Lewis Hamilton | 63 | 309.050 | 56 | SC RF |
| 3 |  Formula 1 Heineken Grande Prémio de Portugal 2021 | Portimão | 2021-05-02 | Lewis Hamilton | Mercedes | Valtteri Bottas | 66 | 306.826 | 60 | SC |
| 4 |  Formula 1 Aramco Gran Premio de España 2021 | Catalunya | 2021-05-09 | Lewis Hamilton | Mercedes | Lewis Hamilton | 66 | 308.424 | 37 | SC |
| 5 |  Formula 1 Grand Prix de Monaco 2021 | Monaco | 2021-05-23 | Max Verstappen | Red Bull | Charles Leclerc | 78 | 260.286 | 19 | |
| 6 |  Formula 1 Azerbaijan Grand Prix 2021 | Baku | 2021-06-06 | Sergio Pérez | Red Bull | Charles Leclerc | 51 | 306.049 | 59 | SC RF |
| 7 |  Formula 1 Emirates Grand Prix de France 2021 | Paul Ricard | 2021-06-20 | Max Verstappen | Red Bull | Max Verstappen | 53 | 309.690 | 22 | |
| 8 |  Formula 1 BWT Grosser Preis der Steiermark 2021 | Red Bull Ring | 2021-06-27 | Max Verstappen | Red Bull | Max Verstappen | 71 | 306.452 | 24 | |
| 9 | Formula 1 BWT Grosser Preis von Österreich 2021 | Red Bull Ring | 2021-07-04 | Max Verstappen | Red Bull | Max Verstappen | 71 | 306.452 | 27 | SC |
| 10 |  Formula 1 Pirelli British Grand Prix 2021 | Silverstone | 2021-07-18 | Lewis Hamilton | Mercedes | Max Verstappen | 52 | 306.198 | 41 | RF |
| 11 |  Formula 1 Rolex Magyar Nagydíj 2021 | Hungaroring | 2021-08-01 | Esteban Ocon | Alpine | Lewis Hamilton | 70 | 306.630 | 52 | SC RF |
| 12 |  Formula 1 Rolex Belgian Grand Prix 2021 | Spa-Francorchamps | 2021-08-29 | Max Verstappen | Red Bull | Max Verstappen | 1 | 6.880 | — | SC RF |
| 13 |  Formula 1 Heineken Dutch Grand Prix 2021 | Zandvoort | 2021-09-05 | Max Verstappen | Red Bull | Max Verstappen | 72 | 306.648 | 29 | |
| 14 | Formula 1 Heineken Gran Premio d'Italia 2021 | Monza | 2021-09-12 | Daniel Ricciardo | McLaren | Max Verstappen | 53 | 306.720 | 22 | SC |
| 15 |  Formula 1 VTB Russian Grand Prix 2021 | Sochi | 2021-09-26 | Lewis Hamilton | Mercedes | Lando Norris | 53 | 309.745 | 39 | |
| 16 |  Formula 1 Rolex Turkish Grand Prix 2021 | Istanbul Park | 2021-10-03 | Valtteri Bottas | Mercedes | Valtteri Bottas | 58 | 309.396 | 20 | |
| 17 |  Formula 1 Aramco United States Grand Prix 2021 | Americas | 2021-10-24 | Max Verstappen | Red Bull | Max Verstappen | 56 | 308.405 | 41 | |
| 18 |  Formula 1 Gran Premio de la Ciudad de México 2021 | Hermanos Rodríguez | 2021-11-07 | Max Verstappen | Red Bull | Valtteri Bottas | 71 | 305.354 | 25 | |
| 19 |  Formula 1 Heineken Grande Prêmio de São Paulo 2021 | José Carlos Pace | 2021-11-14 | Lewis Hamilton | Mercedes | Valtteri Bottas | 71 | 305.909 | 79 | SC |
| 20 |  Formula 1 Ooredoo Qatar Grand Prix 2021 | Lusail | 2021-11-21 | Lewis Hamilton | Mercedes | Lewis Hamilton | 57 | 306.660 | 30 | |
| 21 |  Formula 1 stc Saudi Arabian Grand Prix 2021 | Jeddah | 2021-12-05 | Lewis Hamilton | Mercedes | Lewis Hamilton | 50 | 308.450 | 47 | SC RF |
| 22 |  Formula 1 Etihad Airways Abu Dhabi Grand Prix 2021 | Yas Marina | 2021-12-12 | Max Verstappen | Red Bull | Max Verstappen | 58 | 306.183 | 29 | WDC WCC SC |